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Importantly, bupivacaine inhibits NMDA receptor-mediated synaptic transmission in the dorsal horn of the spinal cord, an area critically involved in central sensitization [284]

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BPC-157 Structure Synonyms Research Areas Gastrointestinal mucosal-integrity signaling: Laboratory studies examining epithelial-barrier maintenance and cellular-response mechanisms in ulcer-induced models Musculoskeletal & connective-tissue signaling: Research evaluating fibroblast migration, collagen organization, and mineralization-associated pathways in tendon, ligament, muscle, and bone models Angiogenic modulation & vascular signaling: Investigation of endothelial-growth-factor regulation and vascular-response coordination in pre-clinical injury systems Neuro-response signaling & CNS research: Experimental models assessing cellular resilience and neural-pathway responses following central-nervous-system injury